SUMMARY
Despite numerous publications on nucleoli, their participation in terminal maturation and
programmed cell death have not been studied extensively. On the other hand, some observations
clearly indicate that terminal maturation and programmed cell death are accompanied by marked
nucleolar changes which reflect the cessation of nucleolar biosynthetic activities. In addition,
nucleolar changes in the course of terminal maturation may precede programmed cell death.
KEY WORDS
nucleolus; erythrocytic and granulocytic precursors; terminal maturation; programmed cell death
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