SUMMARY
Rhythmic changes in a number of haematological characteristics have been described in many
published papers during the 20th and at the beginning of the 21st century. The best known are
circadian rhythms, which are mostly correlated with the light/dark regime, inducing rhythmic
changes in levels of melatonin, synchronised by a suprachiasmatic nucleus and the
retinohypothalamic input. These circadian rhythms in men and diurnal animals have an inverse
relationship to rhythms in nocturnal beings. Some haematological rhythms are modified by other
synchronisers. Knowledge of circadian rhythms in haematological characteristics is important for
both the faultless clinical interpretation of laboratory data and the search for mechanisms
participating in rhythm regulation.
KEY WORDS
circadian rhythm; blood cell; haemopoiesis; clinical significance; synchronization
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