SUMMARY
The professional aim of this project was to map the detection of genotoxicants using cytogenetic
methods. It summarizes the results of four studies carried out at three different workplaces in different
industries. The main aim of the study was also to monitor types of exposure to genotoxicants and their
impact on the human population: The exposure of blast furnace workers in the steel industry to genotoxic
factors; the exposure of coke oven plant workers to genotoxic factors, and the exposure to genotoxic
factors in workplaces in the chemical industry - in particular to heavy metals (Ni, Cd). Cytogenetic
analysis and the micronucleus test are sensitive methods in the field of biomonitoring of human exposure
in industry, and play an important role in the prevention of damage to human health.
KEY WORDS
genotoxicants; micronucleus test; binucleated cells; furnace workers
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