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Journal of APPLIED BIOMEDICINE
ISSN 1214-0287 (on-line)
ISSN 1214-021X (printed)

Volume 4 (2006), No 4, p 171-178




Expectations of biologically active compounds of the genus Magnolia in biomedicine

Jiri Patocka, Jiri Jakl, Anna Strunecka

Address: Jiri Patocka, Department of Radiology and Toxicology, Faculty of Health and Social Studies, University of South Bohemia, 370 01 Ceske Budejovice, Czech Republic
prof.patocka@gmail.com

Received 18th July 2006.
Published online 20th October 2006.

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SUMMARY
Magnolia bark is a highly aromatic herbal material obtained from Magnolia officinalis (and other species) of the family Magnoliaceae. In traditional oriental herbal medicine, particularly Chinese medicine, this drug is used for many purposes, especially as a mild tranquillizer. The principal active compounds are the biphenol compounds, magnolol and honokiol, together with other biologically active compounds, which exert numerous and diverse pharmacological actions. Recent research has produced further evidence for the mechanism of their anti-inflammatory, anti-oxidant, antimicrobial, and antitumour activities, and these will be outlined in this review.

KEY WORDS
herbal tranquillizer; honokiol; Magnolia; magnolol; obovatol; pharmacology


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