SUMMARY
Hyperlipidaemia is one of the major risk factors of cardiovascular complication in diabetes. A study was undertaken
to evaluate the antihyperlipidaemic activity of pterostilbene. Oral administration of pterostilbene (40mg/kg bodyweight)
to streptozotocin-nicotinamide induced diabetic rats for 6 weeks significantly reduced the elevated serum very low density
lipoprotein (VLDL) and low density lipoprotein (LDL)-cholesterol levels and significantly increased the serum
high-density lipoprotein (HDL)-cholesterol level. In addition, pterostilbene also significantly lowered the levels
of triglycerides, phospholipids, free fatty acids and total cholesterol in the serum, liver and kidney of diabetic rats.
KEY WORDS
pterostilbene; lipoproteins; lipids; diabetes
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CITED
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