berger.xml

Obsah souboru

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<Publisher>
	<PublisherInfo>
		<PublisherName>University of South Bohemia, Ceske Budejovice and Versita, Warsaw</PublisherName>
	</PublisherInfo>
	<Journal>
		<JournalInfo JournalType="Journals">
			<JournalPrintISSN>1214-021X</JournalPrintISSN>
			<JournalElectronicISSN>1214-0287</JournalElectronicISSN>
			<JournalTitle>Journal of Applied Biomedicine</JournalTitle>
			<JournalCode>JAB</JournalCode>
			<JournalID>121649</JournalID>
			<JournalURL>http://versita.metapress.com/link.asp?target=journal&amp;id=121649</JournalURL>
		</JournalInfo>
		<Volume>
			<VolumeInfo>
				<VolumeNumber>8</VolumeNumber>
			</VolumeInfo>
			<Issue>
				<IssueInfo IssueType="Regular">
					<IssueNumberBegin>1</IssueNumberBegin>
					<IssueNumberEnd>1</IssueNumberEnd>
					<IssueSupplement>0</IssueSupplement>
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					<IssuePartEnd>0</IssuePartEnd>
					<IssueSequence>000008000120100101</IssueSequence>
					<IssuePublicationDate>
						<CoverDate Year="2010" Month="1" Day="1"/>
						<CoverDisplay>Number 1 / January 2010</CoverDisplay>
					</IssuePublicationDate>
					<IssueID>W87G74W522V0</IssueID>
					<IssueURL>http://versita.metapress.com/link.asp?target=issue&amp;id=W87G74W522V0</IssueURL>
				</IssueInfo>
				<Article ArticleType="Original">
					<ArticleInfo Free="No" ESM="No">
						<ArticleDOI>10.2478/v10136-009-0003-y</ArticleDOI>
						<ArticlePII>0419665782UW67Q6</ArticlePII>
						<ArticleSequenceNumber>3</ArticleSequenceNumber>
						<ArticleTitle Language="En">Alternative haematotoxicological testing</ArticleTitle>
						<ArticleFirstPage>19</ArticleFirstPage>
						<ArticleLastPage>22</ArticleLastPage>
						<ArticleHistory>
							<RegistrationDate>20100127</RegistrationDate>
							<ReceivedDate>20100127</ReceivedDate>
							<Accepted>20100127</Accepted>
							<OnlineDate>20100127</OnlineDate>
						</ArticleHistory>
						<FullTextFileName>0419665782UW67Q6.pdf</FullTextFileName>
						<FullTextURL>http://versita.metapress.com/link.asp?target=contribution&amp;id=0419665782UW67Q6</FullTextURL>
						<Composite>1</Composite>
					</ArticleInfo>
					<ArticleHeader>
						<AuthorGroup>
							<Author AffiliationID="A1">
								<GivenName>Josef</GivenName>
								<Initials/>
								<FamilyName>Berger</FamilyName>
								<Degrees/>
								<Roles/>
							</Author>
							<Affiliation AFFID="A1">
								<OrgDivision/>
								<OrgName>Faculty of Health and Social Studies, University of South Bohemia, České Budějovice, Czech Republic</OrgName>
								<OrgAddress/>
							</Affiliation>
						</AuthorGroup>
						<Abstract Language="En">Standard haematological procedures in preclinical subchronic and chronic toxicity studies are carried out on dogs, rats and other mammals. &lt;i&gt;In vitro&lt;/i&gt; clonic assays CFU-GM, BFU-E, CFU-E, CFU-Mgkr and pluripotent stem cells are used in screening candidate compounds to predict acute cytopenias, but they are not able to reveal the risk of suppression which can develop after repeated administration. No &lt;i&gt;in silico&lt;/i&gt; studies have yet been published in haematotoxicology. More recent haematotoxicological &lt;i&gt;in vivo&lt;/i&gt; models represent invertebrates: they can be used in both ecotoxicology and in the screening of myelotoxicity.</Abstract>
						<KeywordGroup Language="En">
							<Keyword>myelotoxicity</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>alternative testing</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>&lt;i&gt;in vitro&lt;/i&gt;</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>&lt;i&gt;in silico&lt;/i&gt;</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>invetebrate</Keyword>
						</KeywordGroup>
					</ArticleHeader>
				</Article>
			</Issue>
		</Volume>
	</Journal>
</Publisher>