karim.xml

Obsah souboru

<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE Publisher PUBLIC "-//MetaPress//DTD MetaPress 2.0//EN" "http://public.metapress.com/dtd/MPRESS/MetaPressv2.dtd">
<Publisher>
	<PublisherInfo>
		<PublisherName>University of South Bohemia, Ceske Budejovice and Versita, Warsaw</PublisherName>
	</PublisherInfo>
	<Journal>
		<JournalInfo JournalType="Journals">
			<JournalPrintISSN>1214-021X</JournalPrintISSN>
			<JournalElectronicISSN>1214-0287</JournalElectronicISSN>
			<JournalTitle>Journal of Applied Biomedicine</JournalTitle>
			<JournalCode>JAB</JournalCode>
			<JournalID>121649</JournalID>
			<JournalURL>http://versita.metapress.com/link.asp?target=journal&amp;id=121649</JournalURL>
		</JournalInfo>
		<Volume>
			<VolumeInfo>
				<VolumeNumber>8</VolumeNumber>
			</VolumeInfo>
			<Issue>
				<IssueInfo IssueType="Regular">
					<IssueNumberBegin>1</IssueNumberBegin>
					<IssueNumberEnd>1</IssueNumberEnd>
					<IssueSupplement>0</IssueSupplement>
					<IssuePartStart>0</IssuePartStart>
					<IssuePartEnd>0</IssuePartEnd>
					<IssueSequence>000008000120100101</IssueSequence>
					<IssuePublicationDate>
						<CoverDate Year="2010" Month="1" Day="1"/>
						<CoverDisplay>Number 1 / January 2010</CoverDisplay>
					</IssuePublicationDate>
					<IssueID>W87G74W522V0</IssueID>
					<IssueURL>http://versita.metapress.com/link.asp?target=issue&amp;id=W87G74W522V0</IssueURL>
				</IssueInfo>
				<Article ArticleType="Original">
					<ArticleInfo Free="No" ESM="No">
						<ArticleDOI>10.2478/v10136-009-0007-7</ArticleDOI>
						<ArticlePII>0286624322144J18</ArticlePII>
						<ArticleSequenceNumber>7</ArticleSequenceNumber>
						<ArticleTitle Language="En">Inhibition of Ehrlich's ascites carcinoma by ethyl acetate extract from the flower of &lt;i&gt;Calotropis gigantea&lt;/i&gt; L. in mice</ArticleTitle>
						<ArticleFirstPage>47</ArticleFirstPage>
						<ArticleLastPage>54</ArticleLastPage>
						<ArticleHistory>
							<RegistrationDate>20100127</RegistrationDate>
							<ReceivedDate>20100127</ReceivedDate>
							<Accepted>20100127</Accepted>
							<OnlineDate>20100127</OnlineDate>
						</ArticleHistory>
						<FullTextFileName>0286624322144J18.pdf</FullTextFileName>
						<FullTextURL>http://versita.metapress.com/link.asp?target=contribution&amp;id=0286624322144J18</FullTextURL>
						<Composite>1</Composite>
					</ArticleInfo>
					<ArticleHeader>
						<AuthorGroup>
							<Author AffiliationID="A1">
								<GivenName>Muhammad</GivenName>
								<Initials>Rowshanul</Initials>
								<FamilyName>Habib</FamilyName>
								<Degrees/>
								<Roles/>
							</Author>
							<Author AffiliationID="A1">
								<GivenName>Muhammad</GivenName>
								<Initials>Abdul</Initials>
								<FamilyName>Aziz</FamilyName>
								<Degrees/>
								<Roles/>
							</Author>
							<Author AffiliationID="A1">
								<GivenName>Muhammad</GivenName>
								<Initials>Rezaul</Initials>
								<FamilyName>Karim</FamilyName>
								<Degrees/>
								<Roles/>
							</Author>
							<Affiliation AFFID="A1">
								<OrgDivision/>
								<OrgName>Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205, Bangladesh</OrgName>
								<OrgAddress/>
							</Affiliation>
						</AuthorGroup>
						<Abstract Language="En">As part of a scientific appraisal of some of the folkloric and ethnomedical uses of &lt;i&gt;Calotropis gigantea&lt;/i&gt; L. (Family: Asclepiadaceae), the present study was designed to evaluate the antitumour activity of the &lt;i&gt;Calotropis gigantea&lt;/i&gt; flower against Ehrlich's ascites carcinoma (EAC) by using a crude ethyl acetate extract from the flower of &lt;i&gt;Calotropis gigantea&lt;/i&gt; (designated as EECF) in Swiss mice. EECF was administered intraperitoneally at doses of 50, 100 and 200 mg/kg body weight. Bleomycin (0.3 mg/kg) was used as a positive control. EECF treatment significantly decreased both viable tumour cells and body weight gain induced by the tumour burden and prolonged survival time. The haematological and biochemical (glucose, cholesterol, triglyceride, blood urea, ALP, SGPT and SGOT) parameters altered during tumour progression, were also significantly restored in EECF-treated mice. Among the three doses tested, the highest dose was the most potent and comparable with the standard drug bleomycin (0.3 mg/kg). In conclusion, EECF from the &lt;i&gt;Calotropis gigantea&lt;/i&gt; flower has a potent inhibitory effect against EAC cells in a dose dependent manner.</Abstract>
						<KeywordGroup Language="En">
							<Keyword>&lt;i&gt;Calotropis gigantea&lt;/i&gt;</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>Ehrlich's ascites carcinoma</Keyword>
						</KeywordGroup>
						<KeywordGroup Language="En">
							<Keyword>flower and Swiss mice</Keyword>
						</KeywordGroup>
					</ArticleHeader>
				</Article>
			</Issue>
		</Volume>
	</Journal>
</Publisher>